Počet záznamů: 1  

Molecular Xharacterization of Binding of Calcium and Carbohydrates by an Early Activation Antigen of Lymphocytes CD69

  1. 1.
    SYSNO ASEP0170745
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleMolecular Xharacterization of Binding of Calcium and Carbohydrates by an Early Activation Antigen of Lymphocytes CD69
    Author(s) Pavlíček, J. (CZ)
    Sopko, B. (CZ)
    Ettrich, Rüdiger (UEK-B) RID, ORCID, SAI
    Kopecký, J. (CZ)
    Baumruk, V. (CZ)
    Man, P. (CZ)
    Havlíček, V. (CZ)
    Vrbacký, M. (CZ)
    Martínková, L. (CZ)
    Křen, V. (CZ)
    Pospíšil, M. (CZ)
    Bezouška, K. (CZ)
    Source TitleBiochemistry. - : American Chemical Society - ISSN 0006-2960
    Roč. 42, č. 42 (2003), s. 9295-9306
    Number of pages12 s.
    Languageeng - English
    CountryUS - United States
    KeywordsLymphocytes ; antigen ; structure
    Subject RIVEB - Genetics ; Molecular Biology
    R&D ProjectsGA524/00/1275 GA ČR - Czech Science Foundation (CSF)
    GA203/01/1018 GA ČR - Czech Science Foundation (CSF)
    IAA7020006 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    BMH4-CT97-2671 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZMSM 113100001
    MSM 113200002
    AV0Z5020903 - MBU-M
    AnnotationCD69 is the earliest leukocyte activation antigen playing a pivotal role in cellular signaling. Here, we show that a globular C-terminal domain of CD69 belonging to C-type lectins binds calcium through Asp 171, Glu 185, and Glu 187 with Kd = 54 uM.
    WorkplaceGlobal Change Research Institute
    ContactNikola Šviková, svikova.n@czechglobe.cz, Tel.: 511 192 268
    Year of Publishing2004

Počet záznamů: 1  

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