Dendritic cell-based vaccines for therapy of HPV16-induced tumours

0191426 - UMG-J 20010498 RIV US eng J - Článek v odborném periodiku
Bubeník, Jan - Šímová, Jana - Vonka, V. - Šmahel, M. - Mikyšková, Romana - Mendoza, Luis
Dendritic cell-based vaccines for therapy of HPV16-induced tumours.
Advances in Experimental Medicine and Biology. Roč. 495, - (2001), s. 359-363. ISSN 0065-2598. E-ISSN 2214-8019
Grant CEP: GA MZd NC5526; GA ČR GA312/98/0826; GA ČR GA312/99/0542; GA ČR GA301/00/0114; GA ČR GA301/01/0985; GA AV ČR IAA7052002
Výzkumný záměr: CEZ:AV0Z5052915
Klíčová slova: HPV16 * dendritic cells * tumour vaccines
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 0.513, rok: 2000

Experiments were designed for utilization of DC-based cancer vaccines to bypass the lack of efficient tumour antigen presentation on mature DCs by direct loading of DCs with oncoproteins .I.in vitro./I.. The results suggests that the activating and co-stimulatory signals delivered by oncoprotein-pulsed antigen presenting cells should be considered in the construction of vaccines for treatment of human HPV16-associated carcinomas.
Trvalý link: http://hdl.handle.net/11104/0087179