Electrodynamic effects on microtubules

0473515 - ÚFE 2017 RIV DE eng A - Abstrakt
Kučera, Ondřej - Havelka, Daniel - Deriu, M.A. - Cifra, Michal
Electrodynamic effects on microtubules.
European Biophysics Journal With Biophysics Letters. Roč. 44, Jul (2015), s. 169-169. ISSN 0175-7571. E-ISSN 1432-1017.
[10th European-Biophysical-Societies-Association (EBSA) European Biophysics Congress. 18.07.2015-22.07.2015, Dresden]
Grant CEP: GA ČR(CZ) GA15-17102S
Institucionální podpora: RVO:67985882
Klíčová slova: Microtubules * Electrical polarity
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika

Microtubules, polymer tubes of cellular skeleton, are involved in a number of processes servingfor various func-tions. Besides their role in cell mechanics and cell division they also provide enormous substrate for cellular signaling.Here we combine the normal mode analysis of microtubuleswith the electric charge density distribution model of a microtubule. We showinsilicothat each normal mode of a microtubule is accompanied with the high-frequency electro-
magnetic field which is generated by vibrational movement of the charge. Combination of normal modes gives rise to transient phenomenon which can manifest itself as a pulsed excitation propagating along a microtubule.We speculate that such pulses can play role in cell signaling because they are of different nature than pure electrostatic interaction which is screened out on frequencies of normal modes of microtubules
Trvalý link: http://hdl.handle.net/11104/0270631