Počet záznamů: 1  

Rapid diagnosis of methanol poisoning by direct coupling of microextraction techniques to capillary zone electrophoresis

  1. 1.
    0444986 - ÚIACH 2016 RIV SK eng C - Konferenční příspěvek (zahraniční konf.)
    Pantůčková, Pavla - Kubáň, Pavel - Boček, Petr
    Rapid diagnosis of methanol poisoning by direct coupling of microextraction techniques to capillary zone electrophoresis.
    Analytical Methods and Human Health. Conference Proceedings. Bratislava: Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 2015, s. 252-253. ISBN 978-80-971179-5-5.
    [International Conference Analytical Methods and Human Health /20./. Patince (SK), 15.06.2015-18.06.2015]
    Grant CEP: GA ČR(CZ) GA13-05762S
    Grant ostatní: GA AV ČR(CZ) R200311404
    Institucionální podpora: RVO:68081715
    Klíčová slova: methanol poisoning * microextraction techniques * capillary electrophoresis
    Kód oboru RIV: CB - Analytická chemie, separace

    A massive methanol poisoning reported in 2012 in the Czech Republic pointed out the need for development of a robust analytical method suitable for rapid methanol poisoning diagnosis. Formate is the major metabolite in methanol poisoning and is primarily responsible for its toxicity. Formate can also serve as a reliable marker of methanol poisoning since formate concentrations in blood can rise to 10-30 mM in case of acute methanol poisoning, which are almost two orders of magnitude higher than the reference range (0-0.4 mM) reported for blood formate in healthy individuals [1,2]. Several approaches based on capillary zone electrophoresis (CZE) have been reported for formate determination in blood samples and for methanol poisoning diagnosis recently [3-6].
    Trvalý link: http://hdl.handle.net/11104/0247419

     
    Název souboruStaženoVelikostKomentářVerzePřístup
    0444986.pdf34 MBJinápovolen
     
Počet záznamů: 1  

  Tyto stránky využívají soubory cookies, které usnadňují jejich prohlížení. Další informace o tom jak používáme cookies.