Posttranslational modifications of lysine and evolving role in heart pathologies - Recent developments

0442314 - ÚIACH 2015 RIV DE eng J - Článek v odborném periodiku
Šťastná, Miroslava - Van Eyk, J.E.
Posttranslational modifications of lysine and evolving role in heart pathologies - Recent developments.
Proteomics. Roč. 15, 5-6 (2015), s. 1164-1180. ISSN 1615-9853. E-ISSN 1615-9861
Institucionální podpora: RVO:68081715
Klíčová slova: heart pathologies * neddylation * sumoylation * proteomics
Kód oboru RIV: CB - Analytická chemie, separace
Impakt faktor: 4.079, rok: 2015

We discuss the PTMs that occur on lysine, specifically neddylation and sumoylation, and the proteomic approaches that can be applied for identification and quantification. Of interest are the emerging roles for these modifications in heart disease and what can be inferred from studies in other cell types and organs.
Trvalý link: http://hdl.handle.net/11104/0245145