Insect hormones: more than 50-years after the discovery of insect juvenile hormobne analogues (JHA, juvenoids)

0427731 - BC 2015 RIV NL eng J - Článek v odborném periodiku
Sláma, Karel
Insect hormones: more than 50-years after the discovery of insect juvenile hormobne analogues (JHA, juvenoids).
Terrestrial Arthropod Reviews. Roč. 6, č. 4 (2013), s. 257-333. ISSN 1874-9828
Institucionální podpora: RVO:60077344
Klíčová slova: juvenile hormone (JH) * activation neurohormone (AH) pseudojuvenile effects * terpenoid juvenoids
Kód oboru RIV: ED - Fyziologie

The basic theories of insect hormone action were created by insect endocrinologists more than 50-years ago. The theories were conservatively traded and disseminated by industrial chemists, biochemists and molecular biologists, who invaded the field during the extensive search for new juvenile hormone (JH) analogues (juvenoids) in the hope that they could replace toxic insecticides in insect control. The most conservative, leading hormonal theory of Gilbert-Riddiford persists unchanged until this time. It is based on Williams´s conclusions about regulation of insect development by a moulting hormone, which is released from the prothoracic glands (PG) upon their activation from the brain. The developmental changes associated with insect metamorphosis are explained by means of Piepho´s theory about importance of the large-larval, medium-pupal and zero-adult concentrations of JH. The alternative, less renowned Novák-Sláma theory of hormonal regulation postulates that PG are used for other physiological functions and do not release a moulting hormone. The effect of large, medium or zero concentrations of JH is considered to be unimportant, when there is at least a minimum physiologically effective concentration of JH. The theory is based on extensive knowledge of endocrinological literature found in the books by Novák and the discovery of JH bioanalogues in 1961 by Sláma, which was later followed by extensive experience gathered in the work with hundreds of the synthetic JH analogues (juvenoids) in the Czech Republic. According to the theory of Novák-Sláma, the hormonal control of insect development is very simple. It is executed by interactions of the two hormones of the central neuroendocrine system. The first is a neuropeptide from the corpora cardiaca which advances the developmental schedule from one genetically determined ontogenetic position to the next. The second hormone is released from the corpora allata.
Trvalý link: http://hdl.handle.net/11104/0234303