Modified approach for preparing (E)-stilbenes related to resveratrol, and evaluation of their potential immunobiological effects

0342940 - ÚOCHB 2011 RIV CZ eng J - Článek v odborném periodiku
Šmidrkal, J. - Harmatha, Juraj - Buděšínský, Miloš - Vokáč, Karel - Zídek, Zdeněk - Kmoníčková, Eva - Merkl, R. - Filip, V.
Modified approach for preparing (E)-stilbenes related to resveratrol, and evaluation of their potential immunobiological effects.
Collection of Czechoslovak Chemical Communications. Roč. 75, č. 2 (2010), s. 175-186. ISSN 0010-0765
Grant CEP: GA ČR(CZ) GA203/07/1227
Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50390512
Klíčová slova: resveratrol * pterostilbene * pinosylvin
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.853, rok: 2010

Our approach allowed obtaining largely hydroxy- and methoxystilbenes, formed as (E)-isomers only. The hydroxymethoxystilbenes (as e.g. pterostilbene) were prepared using specific OH protection and deprotection. The method is suitable for preparing such compounds in a large amount. Effects of the obtained stilbenoids on immunobiological responses were tested under in vitro conditions.
Trvalý link: http://hdl.handle.net/11104/0185541