Adsorption and two-dimensional condensation of 5-methylcytosine

0327283 - BFÚ 2010 RIV CH eng J - Článek v odborném periodiku
Fojt, Lukáš - Vetterl, Vladimír - Doneux, T.
Adsorption and two-dimensional condensation of 5-methylcytosine.
Bioelectrochemistry. Roč. 75, č. 2 (2009), s. 89-94. ISSN 1567-5394. E-ISSN 1878-562X
Grant CEP: GA AV ČR(CZ) KAN200040651; GA MŠMT(CZ) LC06035; GA ČR(CZ) GA202/08/1688
Grant ostatní: GA MŠk(CZ) 1M0528; GA ČR(CZ) GP310/07/P480
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: hanging mercury drop electrode * 5-methylcytosine * 2D condensation
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 2.652, rok: 2009

Purine and pyrimidine derivatives occurring in nucleic acids posses an extraordinary high ability of self-association at the electrode surface and can form there by a two-dimensional (2D) condensation a monomolecular compact film (self-assembled monolayer-SAM). The effects of methyl substituent on the 2D condensation were studied using the 5-methylcytosine molecule which is involved in gene silencing and has a great biological impact.
Trvalý link: http://hdl.handle.net/11104/0174131