Improvement of the accuracy by the measurement of the electrical cell membrane parameters

0142309 - FGU-C 20020031 RIV CZ eng J - Článek v odborném periodiku
Rohlíček, Vojtěch - Rech, František
Improvement of the accuracy by the measurement of the electrical cell membrane parameters.
Physiological Research. Roč. 51, č. 2 (2002), s. 169-177. ISSN 0862-8408. E-ISSN 1802-9973
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: patch clamp technique * electrical parameters of the cell membrane * memebrane capacity
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 0.984, rok: 2002

The electrical parameters of the cell membrane are mostly estimated employing ac methods. The measurement is based on the analysis of the current(s) flowing through an access resistance and the membrane. A current/potential transducer is used at the input of the device. The parameters of this transducer, especially its feedback capacity, degrades the accuracy of the measurement and hence diminishes the suppression of mutual influences of the individual parameters. The paper suggest a possible software correction and is supplemented by remarks for practical application.
Trvalý link: http://hdl.handle.net/11104/0040015