0576578 - BC 2024 RIV GB eng A - Abstrakt
Majstorović, Jovana - Klak, J. - Maciuszek, M. - Chan, J.T.H.
Alien vs Predator: Immune responses of the common carp Cyprinus carpio red blood cells in bacterial infection with Aeromonas hydrophila include pro-inflammatory responses, production of the reactive oxygen species (ROS) and phagocytosis.
Developmental and Comparative Immunology. Elsevier. Roč. 148, NOV (2023), č. článku 104974. ISSN 0145-305X. E-ISSN 1879-0089.
[15th Congress of the International-Society-of-Developmental-and-Comparative-Immunology (ISDCI). 28.09.2023, Wageningen]
Institucionální podpora: RVO:60077344
Klíčová slova: AEROMONAS HYDROPHILA * Cyprinus carpio * common carp
Obor OECD: Veterinary science
Web výsledku:
https://www.sciencedirect.com/science/article/pii/S0145305X23011278

Knowingthatour,erythrocyteshaveaminimalcapacityfortranscription andproteinsynthesisasaresultoflossofthenucleusthroughoutthe maturation,redbloodcellshavealwaysbeenoverlookedandneglectedin theirroleinnotonlythediseasebutalsoasimmunemodulatorsofboth innateandadaptiveimmunity.Previously,weobservedthestrongproinflammatoryimmuneresponsesgeneratedbytheredbloodcellsin parasiticdiseasehencethemajoraimofthisprojectwastoevaluatethe immuneresponseoftheRBCsinthebacterialinfection,toobserve whethertheRBCshavetheabilitytodistinguishdifferentpathogenandif so,whatimmunemechanismsdotheydeploy.Forthatpurpose,wehave performedaseriesofco-cultureexperimentswiththeRBCsofC.carpio exposedtotheAeromonashydrophilaaswellastheinvivoinfectionin differentconcentrations.
Trvalý link: https://hdl.handle.net/11104/0351114