Počet záznamů: 1  

Bone marrow adipose tissue: Role in bone remodeling and energy metabolism

  1. 1.
    0547572 - FGÚ 2022 RIV GB eng J - Článek v odborném periodiku
    Tencerová, Michaela - Ferenčáková, Michaela - Kassem, M.
    Bone marrow adipose tissue: Role in bone remodeling and energy metabolism.
    Best Practice & Research Clinical Endocrinology & Metabolism. Roč. 35, č. 4 (2021), č. článku 101545. ISSN 1521-690X. E-ISSN 1532-1908
    Grant CEP: GA ČR(CZ) GA20-03586S
    Grant ostatní: Novo Nordisk Fonden(DK) NNF20SA0066174
    Institucionální podpora: RVO:67985823
    Klíčová slova: bone marrow adipose tissue * bone marrow mesenchymal stem cells * energy metabolism * metabolic pathways
    Obor OECD: Cell biology
    Impakt faktor: 5.667, rok: 2021
    Způsob publikování: Omezený přístup
    https://doi.org/10.1016/j.beem.2021.101545

    Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent bystander that fills empty space left in bone marrow following age-related decrease in hematopoiesis. However, recently new discoveries revealed BMAT as a secretory and metabolically active organ contributing to bone and whole-body energy metabolism. BMAT exhibits metabolic functions distinct from extramedullary adipose depots, relevant to its role in regulation of energy metabolism and its contribution to fracture risk observed in metabolic bone diseases. This review discusses novel insights of BMAT with particular emphasis on its contribution to the regulation of bone homeostasis. We also discuss the role of BMAT in regulation of fuel utilization and energy use that affect skeletal stem cell functions.
    Trvalý link: http://hdl.handle.net/11104/0323780

     
     
Počet záznamů: 1  

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