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A new role for 14-3-3 protein in steroidogenesis

  1. 1.
    0533044 - FGÚ 2021 GB eng J - Článek v odborném periodiku
    Obšilová, Veronika - Obšil, Tomáš
    A new role for 14-3-3 protein in steroidogenesis.
    FEBS Journal. Roč. 287, č. 18 (2020), s. 3921-3924. ISSN 1742-464X. E-ISSN 1742-4658
    Grant CEP: GA ČR(CZ) GA20-00058S; GA ČR(CZ) GA19-00121S
    Institucionální podpora: RVO:67985823
    Klíčová slova: 14‐3‐3 protein * phosphorylation * STARD1 * START domain * steroidogenesis
    Obor OECD: Biochemistry and molecular biology
    Impakt faktor: 5.542, rok: 2020
    Způsob publikování: Open access
    https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15507

    Steroidogenic acute regulatory protein (STARD1) is regulated by phosphorylation and 14‐3‐3 protein binding. STARD1 is a key player in cholesterol transport in mitochondria, and its regulation is not fully understood. Tugaeva et al. provide novel insights on the site‐specific phosphorylation and subsequent 14‐3‐3‐dependent regulation of STARD1 function. These results may help us understand the mechanism behind the regulation of steroidogenesis.
    Trvalý link: http://hdl.handle.net/11104/0311544

     
     
Počet záznamů: 1