Počet záznamů: 1  

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA

  1. 1. 0482517 - UOCHB-X 2018 RIV GB eng J - Článek v odborném periodiku
    Balintová, Jana - Simonova, Anna - Bialek-Pietras, M. - Olejniczak, A. - Lesnikowski, Z. J. - Hocek, Michal
    Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.
    Bioorganic and Medicinal Chemistry Letters. Roč. 27, č. 21 (2017), s. 4786-4788 ISSN 0960-894X
    Grant CEP: GA ČR GBP206/12/G151
    Grant ostatní:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institucionální podpora: RVO:61388963
    Klíčová slova: nucleotides * nucleoside triphosphates * carboranes * DNA polymerase * oligonucleotides
    Kód oboru RIV: CC - Organická chemie
    Obor OECD: Organic chemistry
    Impakt faktor: 2.442, rok: 2017

    5-[(p-Carborane-2-yl) ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases.
    Trvalý link: http://hdl.handle.net/11104/0277943