Počet záznamů: 1  

A Waking Review: Old and Novel Insights into the Spore Germination in Streptomyces

  1. 1. 0482240 - MBU-M 2018 RIV CH eng J - Článek v odborném periodiku
    Bobek, Jan - Šmídová, Klára - Čihák, M.
    A Waking Review: Old and Novel Insights into the Spore Germination in Streptomyces.
    Frontiers in Microbiology. Roč. 8, NOV 13 (2017), s. 1-12, č. článku 2205. ISSN 1664-302X
    Grant CEP: GA MŠk(CZ) LM2015055
    Institucionální podpora: RVO:61388971
    Klíčová slova: dormancy * germination * Streptomyces
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Obor OECD: Microbiology
    Impakt faktor: 4.019, rok: 2017

    The complex development undergone by Streptomyces encompasses transitions from vegetative mycelial forms to reproductive aerial hyphae that differentiate into chains of single-celled spores. Whereas their mycelial life - connected with spore formation and antibiotic production - is deeply investigated, spore germination as the counterpoint in their life cycle has received much less attention. Still, germination represents a system of transformation from metabolic zero point to a new living lap. There are several aspects of germination that may attract our attention: (1) Dormant spores are strikingly well-prepared for the future metabolic restart, they possess stable transcriptome, hydrolytic enzymes, chaperones, and other required macromolecules stabilized in a trehalose milieu, (2) Germination itself is a specific sequence of events leading to a complete morphological remodeling that include spore swelling, cell wall reconstruction, and eventually germ tube emergences, (3) Still not fully unveiled are the strategies that enable the process, including a single cell's signal transduction and gene expression control, as well as intercellular communication and the probability of germination across the whole population. This review summarizes our current knowledge about the germination process in Streptomyces, while focusing on the aforementioned points.
    Trvalý link: http://hdl.handle.net/11104/0277621