Počet záznamů: 1
Accuracy of rate coding: When shorter time window and higher spontaneous activity help
- 1.0474687 - FGU-C 2018 RIV US eng J - Článek v odborném periodiku
Leváková, Marie - Tamborrino, M. - Košťál, Lubomír - Lánský, Petr
Accuracy of rate coding: When shorter time window and higher spontaneous activity help.
Physical Review E. Roč. 95, č. 2 (2017), č. článku 022310. ISSN 2470-0045
Grant CEP: GA ČR(CZ) GA15-08066S; GA MŠk(CZ) 7AMB17AT048
Institucionální podpora: RVO:67985823
Klíčová slova: rate coding * observation window * spontaneous activity * Fisher information * perfect integrate-and-fire model * Wiener process
Kód oboru RIV: BB - Aplikovaná statistika, operační výzkum
Obor OECD: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impakt faktor: 2.284, rok: 2017
It is widely accepted that neuronal firing rates contain a significant amount of information about the stimulus intensity. Nevertheless, theoretical studies on the coding accuracy inferred from the exact spike counting distributions are rare. We present an analysis based on the number of observed spikes assuming the stochastic perfect integrate-and-fire model with a change point, representing the stimulus onset, for which we calculate the corresponding Fisher information to investigate the accuracy of rate coding. We analyze the effect of changing the duration of the time window and the influence of several parameters of the model, in particular the level of the presynaptic spontaneous activity and the level of random fluctuation of the membrane potential, which can be interpreted as noise of the system. The results show that the Fisher information is nonmonotonic with respect to the length of the observation period. This counterintuitive result is caused by the discrete nature of the count of spikes. We observe also that the signal can be enhanced by noise, since the Fisher information is nonmonotonic with respect to the level of spontaneous activity and, in some cases, also with respect to the level of fluctuation of the membrane potential.
Trvalý link: http://hdl.handle.net/11104/0271681