Per-2,3-O-alkylated beta-cyclodextrin duplexes connected with disulfide bonds

0474129 - ÚOCHB 2018 RIV GB eng J - Článek v odborném periodiku
Tatar, Ameneh - Grishina, Anastasia - Buděšínský, Miloš - Kraus, Tomáš
Per-2,3-O-alkylated beta-cyclodextrin duplexes connected with disulfide bonds.
Supramolecular Chemistry. Roč. 29, č. 1 (2017), s. 40-48. ISSN 1061-0278. E-ISSN 1029-0478
Grant CEP: GA MŠMT LD12019
Grant ostatní: COST(XE) CM1005
Institucionální podpora: RVO:61388963
Klíčová slova: cyclodextrins * inclusion complexes * disulfide bonds
Obor OECD: Organic chemistry
Impakt faktor: 1.451, rok: 2017

Per-2,3-di-O-methyl- and per-2,3-di-O-allyl-b-cyclodextrin duplexes held by two disulfide bonds between their primary faces have been prepared. Permethylation significantly increased the solubility of the cyclodextrin duplexes in a wide range of solvents from water to chlorinated hydrocarbons. Per-2,3-di-O-methylated duplexes are able to form inclusion complexes with organic molecules in aqueous solutions, yet the stability constants are lower by 4-5 orders of magnitude as compared to analogous non-alkylated b-cyclodextrin duplexes.
Trvalý link: http://hdl.handle.net/11104/0272679