Počet záznamů: 1  

The interplay between biological and physical scenarios of bacterial death induced by non-thermal plasma

  1. 1.
    0470525 - FZU-D 2017 RIV GB eng J - Článek v odborném periodiku
    Lunov, Oleg - Zablotskyy, Vitaliy A. - Churpita, Olexandr - Jäger, Aleš - Polívka, Leoš - Syková, E. - Dejneka, Alexandr - Kubinová, Šárka
    The interplay between biological and physical scenarios of bacterial death induced by non-thermal plasma.
    Biomaterials. Roč. 82, Mar (2016), s. 71-83. ISSN 0142-9612
    Grant CEP: GA MŠk LO1409; GA MŠk(CZ) LM2011026
    Grant ostatní:FUNBIO(XE) CZ.2.16/3.1.00/21568; AV ČR(CZ) Fellowship J. E. Purkyně
    Institucionální podpora: RVO:68378271
    Klíčová slova: non-thermal plasma * bacteria * cytotoxicity * apoptosis * bacterial inactivation * reactive oxygen species (ROS)
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 8.402, rok: 2016

    Direct interactions of plasma matter with living cells and tissues can dramatically affect their functionality, initiating many important effects from cancer elimination to bacteria deactivation. However, the physical mechanisms and biochemical pathways underlying the effects of non-thermal plasma on bacteria and cell fate have still not been fully explored. Here, we report on the molecular mechanisms of non-thermal plasma-induced bacteria inactivation in both Gram-positive and Gram-negative strains. We demonstrate that depending on the exposure time plasma induces either direct physical destruction of bacteria or triggers programmed cell death (PCD) that exhibits characteristic features of apoptosis. The interplay between physical disruption and PCD is on the one hand driven by physical plasma parameters, and on the other hand by biological and physical properties of bacteria.
    Trvalý link: http://hdl.handle.net/11104/0268132