0467846 - MBÚ 2017 RIV US eng J - Journal Article
Přichystal, Jakub - Schug, K. A. - Lemr, Karel - Novák, Jiří - Havlíček, Vladimír
Structural Analysis of Natural Products.
Analytical Chemistry. Roč. 88, č. 21 (2016), s. 10338-10346. ISSN 0003-2700. E-ISSN 1520-6882
R&D Projects: GA MŠMT(CZ) LO1509; GA MŠMT(CZ) LH14064; GA ČR(CZ) GA16-20229S
Institutional support: RVO:61388971
Keywords : IONIZATION-MASS-SPECTROMETRY * BIOSYNTHETIC GENE CLUSTERS * STRUCTURE ELUCIDATION
Subject RIV: EE - Microbiology, Virology
Impact factor: 6.320, year: 2016 ; AIS: 1.403, rok: 2016
DOI: https://doi.org/10.1021/acs.analchem.6b02386

Current mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray diffraction are presented as structure elucidation tools for analytical chemistry of natural products. Discovering new molecular entities combined with dereplication of known organic compounds represent prerequisites for biological assays and for respective applications as pharmaceuticals or molecular markers. Liquid chromatography is briefly addressed with respect to its use in mass spectrometry- and nuclear magnetic resonance-based metabolomics studies.
Permanent Link: http://hdl.handle.net/11104/0266200