Počet záznamů: 1

Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding

  1. 1.
    0464967 - FGU-C 2017 RIV US eng J - Článek v odborném periodiku
    Leváková, Marie - Tamborrino, M. - Košťál, Lubomír - Lánský, Petr
    Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding.
    Neural Computation. Roč. 28, č. 10 (2016), s. 2162-2180 ISSN 0899-7667
    Grant CEP: GA MŠk 7AMB15AT010; GA ČR(CZ) GA15-08066S
    Institucionální podpora: RVO:67985823
    Klíčová slova: neural coding * first-spike latency * spontaneous activity
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 1.938, rok: 2016

    The time to the first spike after stimulus onset typically varies with the stimulation intensity. Experimental evidence suggests that neural systems use such response latency to encode information about the stimulus. We investigate the decoding accuracy of the latency code in relation to the level of noise in the form of presynaptic spontaneous activity. Paradoxically, the optimal performance is achieved at a nonzero level of noise and suprathreshold stimulus intensities. We argue that this phenomenon results from the influence of the spontaneous activity on the stabilization of the membrane potential in the absence of stimulation. The reported decoding accuracy improvement represents a novel manifestation of the noise-aided signal enhancement.
    Trvalý link: http://hdl.handle.net/11104/0263707