Počet záznamů: 1  

Supramolecular structures and self-association processes in polymer systems

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    0463568 - ÚMCH 2017 RIV CZ eng J - Článek v odborném periodiku
    Hrubý, Martin - Filippov, Sergey K. - Štěpánek, Petr
    Supramolecular structures and self-association processes in polymer systems.
    Physiological Research. Roč. 65, Suppl. 2 (2016), S165-S178. ISSN 0862-8408. E-ISSN 1802-9973
    Grant CEP: GA MŠk(CZ) LO1507
    Institucionální podpora: RVO:61389013
    Klíčová slova: copolymers * nanoparticles * phase separation
    Kód oboru RIV: CD - Makromolekulární chemie
    Impakt faktor: 1.461, rok: 2016
    http://www.biomed.cas.cz/physiolres/pdf/65%20Suppl%202/65_S165.pdf

    Self-organization in a polymer system appears when a balance is achieved between long-range repulsive and short-range attractive forces between the chemically different building blocks. Block copolymers forming supramolecular assemblies in aqueous media represent materials which are extremely useful for the construction of drug delivery systems especially for cancer applications. Such formulations suppress unwanted physico-chemical properties of the encapsulated drugs, modify biodistribution of the drugs towards targeted delivery into tissue of interest and allow triggered release of the active cargo. In this review, we focus on general principles of polymer self-organization in solution, phase separation in polymer systems (driven by external stimuli, especially by changes in temperature, pH, solvent change and light) and on effects of copolymer architecture on the self-assembly process.
    Trvalý link: http://hdl.handle.net/11104/0264455

     
     
Počet záznamů: 1