Počet záznamů: 1  

Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses

  1. 1.
    0458688 - UOCHB-X 2017 RIV DE eng J - Článek v odborném periodiku
    Štěpánová, Sille - Kašička, Václav
    Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses.
    Journal of Separation Science. Roč. 39, č. 1 (2016), s. 198-211. ISSN 1615-9306
    Grant CEP: GA ČR(CZ) GA13-17224S; GA ČR(CZ) GA15-01948S
    Institucionální podpora: RVO:61388963
    Klíčová slova: capillary electrophoresis * mass spectrometry * microchip electrophoresis * peptidomics * proteomics
    Kód oboru RIV: CB - Analytická chemie, separace
    Impakt faktor: 2.557, rok: 2016

    This review presents recent developments and applications of capillary and microchip electromigration methods in proteomics and peptidomics. Sample preparation methods as well as instrumental innovations in the coupling of these advanced electromigration methods with mass spectrometry detection employed in proteomic and peptidomic analyses are presented. Interesting applications of various capillary electromigration methods in bottom-up as well as top-down proteomics, including investigation of post-translational modifications of proteins are described. In addition, several examples of the use of capillary electromigration methods combined with mass spectrometry detection in clinical proteomics and peptidomics are demonstrated.
    Trvalý link: http://hdl.handle.net/11104/0258941