Počet záznamů: 1  

Activity of telomerase and telomeric length in Aphis mellifera

  1. 1. 0451756 - BC-A 2017 RIV US eng J - Článek v odborném periodiku
    Korandová, Michala - Čapková Frydrychová, Radmila
    Activity of telomerase and telomeric length in Aphis mellifera.
    Chromosoma. Roč. 125, č. 3 (2016), s. 405-411. ISSN 0009-5915
    Grant CEP: GA ČR GA14-07172S
    Grant ostatní:GA JU(CZ) 052/2013/P; European Union Seventh Framework(CZ) 316304
    Program:FP7
    Institucionální podpora: RVO:60077344
    Klíčová slova: telomere * telomerase * Apis mellifera
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 4.414, rok: 2016

    We report an analysis of telomerase activity and telomere length in the honeybee, Apis mellifera. Telomerase activity was found to be regulated in a development and caste-specific manner. During the development of somatic tissues of larval drones and workers, telomerase activity declined to 10 % of its level in embryos and remained low during pupal and adult stages but was upregulated in testes of late pupae. Upregulation of telomerase activity was observed in the ovaries of late pupal queens. Compared to workers and drones, queens displayed higher levels of telomerase activity. Southern hybridization of terminal TTAGG fragments revealed a high variability of telomeric length between different individuals, although the same pattern of hybridization signals was observed in different tissues of each individual.
    Trvalý link: http://hdl.handle.net/11104/0261005