Počet záznamů: 1  

Effect of low doses of herbicide paraquat on antioxidant defense in Drosophila

  1. 1.
    0451715 - BC 2016 RIV US eng J - Článek v odborném periodiku
    Krůček, Tomáš - Korandová, Michala - Szakosová, K. - Šerý, Michal - Čapková Frydrychová, Radmila
    Effect of low doses of herbicide paraquat on antioxidant defense in Drosophila.
    Archives of Insect Biochemistry and Physiology. Roč. 88, č. 4 (2015), s. 235-248. ISSN 0739-4462
    Grant CEP: GA ČR GA14-07172S
    Grant ostatní:GA JU(CZ) 038/2014/P; GA JU(CZ) 052/2013/P; European Union Seventh Framework Programme(CZ) 316304
    Program:FP7-REGPOT
    Institucionální podpora: RVO:60077344
    Klíčová slova: Drosophila * oxidative stress * paraquat
    Kód oboru RIV: CE - Biochemie
    Impakt faktor: 1.357, rok: 2015
    http://onlinelibrary.wiley.com/doi/10.1002/arch.21222/epdf

    Despite a high toxicity, paraquat is one of the most widely used herbicides in the world. The study evaluated the effect of paraquat exposure on antioxidant response in Drosophila melanogaster. When we examined the /nenzymatic activity of superoxide dismutase and catalase in flies exposed to a wide range of paraquat concentrations (0.25 μM to 25 mM), biphasic dose–/nresponse curve with the peak at 2.5 μM paraquat was revealed. Males revealed higher susceptibility to paraquat exposure, displaying higher lethality, increased levels of superoxide dismutase activity, and increased peroxide /nlevels than found in females. Because susceptibility to paraquat was enhanced by mating, the study supports the hypothesis of elevation of stress sensitivity as a physiological cost of reproduction.
    Trvalý link: http://hdl.handle.net/11104/0256862