Počet záznamů: 1
Science of Synthesis
- 1.0445914 - MBÚ 2016 RIV DE eng M - Část monografie knihy
Martínková, Ludmila - Veselá, Alicja Barbara
Hydrolysis of Nitriles to Carboxylic Acids.
Science of Synthesis. Stuttgart: Georg Thieme Verlag KG Stuttgart, 2015 - (Faber, K.; Fessner, W.; Turner, N.), s. 277-302. Biocatalysis in Organic Synthesis 1. ISBN 978-3-13-174131-8
Grant CEP: GA ČR(CZ) GAP504/11/0394
Institucionální podpora: RVO:61388971
Klíčová slova: nitrilase * nitrile hydratase * amidase
Kód oboru RIV: CE - Biochemie
The biocatalytic hydrolysis of nitriles to carboxylic acids is catalyzed by either a nitrilase or a bienzymatic cascade system comprised of a nitrile hydratase and an amidase. Using the same enzymes, amides can be obtained as side products (by nitrilases) or as intermediates (by nitrile hydratases). The tendency to form amides is characteristic of some nitrilases and depends also on the substrate structure, a bulky or an electrophilic group enhancing the turnover of nitrile into amide.
Trvalý link: http://hdl.handle.net/11104/0257912
Počet záznamů: 1