0437648 - FGÚ 2015 RIV CZ eng J - Článek v odborném periodiku
Brožíčková, Carole - Mikulecká, Anna - Otáhal, Jakub
Effect of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, on behavioral and physiological parameters.
Physiological Research. Roč. 63, č. 5 (2014), s. 637-648. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA ČR(CZ) GAP303/10/0999; GA ČR(CZ) GPP304/11/P386; GA ČR(CZ) GBP304/12/G069
Výzkumný záměr: CEZ:AV0Z50110509
Institucionální podpora: RVO:67985823
Klíčová slova: 7-nitroindazole * open field test * ladder rung walking test * brain excitability * blood gas analysis * rat
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 1.293, rok: 2014 ; AIS: 0.403, rok: 2014

Present study elucidate effect of an inhibitor of neuronal nitric oxide synthase on behavioral and physiological parameters. Our results show that in conscious rats 7-NI induces a rise in arterial blood pressure and significantly alters level of blood gases. 7-NI moreover affects locomotion and exploratory activity and induces walking incoordination and increases cortical excitability as revealed by electrophysiology
Trvalý link: http://hdl.handle.net/11104/0241162