Počet záznamů: 1  

Delay in the Diagnosis and Treatment of Pulmonary Tuberculosis in Uzbekistan: A Cross-Sectional Study

  1. 1.
    0435975 - ÚI 2015 RIV GB eng J - Článek v odborném periodiku
    Belkina, T.V. - Khojiev, D.S. - Tillyashaykhov, M.N. - Tigay, Z.N. - Kudenov, M.U. - Duintjer Tebbens, Jurjen - Vlček, J.
    Delay in the Diagnosis and Treatment of Pulmonary Tuberculosis in Uzbekistan: A Cross-Sectional Study.
    Bmc Infectious Diseases. Roč. 14, November (2014), article 624. E-ISSN 1471-2334
    Grant ostatní: SVV UK(CZ) 260 066
    Institucionální podpora: RVO:67985807
    Klíčová slova: cross-sectional study * pulmonary tuberculosis * self-medication * Uzbekistan
    Kód oboru RIV: FR - Farmakologie a lékárnická chemie
    Impakt faktor: 2.613, rok: 2014

    Background: Early diagnosis and prompt effective therapy are crucial for the prevention of tuberculosis (TB) transmission, particularly in regions with high levels of multi-drug resistant TB. This study aimed to evaluate the extent of delay in diagnosis and treatment of TB in Uzbekistan and identify associated risk factors. Methods: A cross-sectional study was performed on hospital patients with newly diagnosed TB. The time between the onset of respiratory symptoms and initiation of anti-TB treatment was assessed and delays were divided into patient, health system and total delays. Univariable and multivariable logistic regression analysis was used to evaluate determinants of diagnostic and treatment delay. Results: Among 538 patients enrolled, the median delay from onset of symptoms until treatment with anti-TB drugs was 50 days. Analysis of the factors affecting health-seeking behaviour and timely treatment showed the presence of the patient factor. Self-medication was the first health-seeking action for 231 (43%) patients and proved to be a significant predictor of delay (p = 0.005), as well as coughing (p = 0.009), loss of weight (p = 0.001), and visiting private and primary healthcare facilities (p = 0.03 and p = 0.02, respectively). Conclusion: TB diagnostic and treatment delay was mainly contributed to by patient delay and should be reduced through increasing public awareness of TB symptoms and improving public healthseeking behaviour for timely initiation of anti-TB treatment. Efforts should be made to minimise irrational use of antibiotics and support interventions to restrict over-the-counter availability of antibiotics.
    Trvalý link: http://hdl.handle.net/11104/0239819

     
     
Počet záznamů: 1  

  Tyto stránky využívají soubory cookies, které usnadňují jejich prohlížení. Další informace o tom jak používáme cookies.