0435673 - MBÚ 2015 RIV GB eng J - Článek v odborném periodiku
Holubová, M. - Lysák, D. - Vlas, T. - Vannucci, Luca - Jindra, P.
Expanded cryopreserved mesenchymal stromal cells as an optimal source for graft-versus-host disease treatment.
Biologicals. Roč. 42, č. 3 (2014), s. 139-144. ISSN 1045-1056. E-ISSN 1095-8320
Institucionální podpora: RVO:61388971
Klíčová slova: Mesenchymal stromal cells * Cryopreservation * Immunomodulation
Kód oboru RIV: EC - Imunologie
Impakt faktor: 1.209, rok: 2014 ; AIS: 0.419, rok: 2014
DOI: https://doi.org/10.1016/j.biologicals.2014.01.003

Mesenchymal stromal cells (MSC) are fibroblast-like cells present in different types of tissues. Their immunomodulatory potential represents a promising method for post-transplant immunotherapy in the treatment of GVHD (graft-versus-host disease) with suboptimal response to standard immunosuppression. In this study we tested influence of 1-8 month-long cryopreservation on ability of MSC to suppress activation of non-specifically stimulated lymphocytes.
Trvalý link: http://hdl.handle.net/11104/0239625