Počet záznamů: 1  

Diastereoselective and one-pot synthesis of trans-isoquinolonic acids via three-component condensation of homophthalic anhydride, aldehydes, and ammonium acetate catalyzed by aspartic acid

  1. 1.
    0435612 - FZU-D 2015 RIV GB eng J - Článek v odborném periodiku
    Ghorbani-Choghamarani, A. - Hajjami, M. - Norouzi, M. - Abbasityula, Y. - Eigner, Václav - Dušek, Michal
    Diastereoselective and one-pot synthesis of trans-isoquinolonic acids via three-component condensation of homophthalic anhydride, aldehydes, and ammonium acetate catalyzed by aspartic acid.
    Tetrahedron. Roč. 69, č. 32 (2013), s. 6541-6544. ISSN 0040-4020
    Grant ostatní:AV ČR(CZ) AP0701
    Program:Akademická prémie - Praemium Academiae
    Institucionální podpora: RVO:68378271
    Klíčová slova: isoquinolonic acid * diastereoselective * aldehyde * homophthalic anhydride * ammonium acetate
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 2.817, rok: 2013

    Aspartic acid has been developed as a versatile and highly efficient organocatalyst for the three component combination of homophthalic anhydride, aldehydes, and ammonium acetate to afford transisoquinolonic acids. The reactions were carried out in acetonitrile under reflux conditions. Aspartic acid as an efficient organocatalyst exhibits dramatically improved diastereoselectivity compared with previously reported catalysts for this synthetic strategy.
    Trvalý link: http://hdl.handle.net/11104/0239422