Počet záznamů: 1  

Direct laser writing of synthetic poly(amino acid) hydrogels and poly(ethylene glycol) diacrylates by two-photon polymerization

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    0433911 - ÚMCH 2015 RIV NL eng J - Článek v odborném periodiku
    Käpylä, E. - Sedlačík, Tomáš - Aydogan, D. B. - Viitanen, J. - Rypáček, František - Kellomäki, M.
    Direct laser writing of synthetic poly(amino acid) hydrogels and poly(ethylene glycol) diacrylates by two-photon polymerization.
    Materials Science & Engineering C-Materials for Biological Applications. Roč. 43, 1 October (2014), s. 280-289. ISSN 0928-4931. E-ISSN 1873-0191
    Grant CEP: GA ČR(CZ) GAP108/11/1857
    Institucionální podpora: RVO:61389013
    Klíčová slova: direct laser writing * two-photon polymerization * microfabrication
    Kód oboru RIV: CD - Makromolekulární chemie
    Impakt faktor: 3.088, rok: 2014

    The additive manufacturing technique of direct laser writing by two-photon polymerization (2PP-DLW) enables the fabrication of three-dimensional microstructures with superior accuracy and flexibility. When combined with biomimetic hydrogel materials, 2PP-DLW can be used to recreate the microarchitectures of the extracellular matrix. However, there are currently only a limited number of hydrogels applicable for 2PP-DLW. In order to widen the selection of synthetic biodegradable hydrogels, in this work we studied the 2PP-DLW of methacryloylated and acryloylated poly(α-amino acid)s (poly(AA)s). The performance of these materials was compared to widely used poly(ethylene glycol) diacrylates (PEGdas) in terms of polymerization and damage thresholds, voxel size, line width, post-polymerization swelling and deformation. We found that both methacryloylated and acryloylated poly(AA) hydrogels are suitable to 2PP-DLW with a wider processing window than PEGdas. The poly(AA) with the highest degree of acryloylation showed the greatest potential for 3D microfabrication.
    Trvalý link: http://hdl.handle.net/11104/0238094

     
     
Počet záznamů: 1  

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