Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites

0431595 - FGÚ 2015 RIV NZ eng J - Článek v odborném periodiku
Filová, Elena - Suchý, Tomáš - Sucharda, Zbyněk - Šupová, Monika - Žaloudková, Margit - Balík, Karel - Lisá, Věra - Šlouf, Miroslav - Bačáková, Lucie
Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites.
International Journal of Nanomedicine. Roč. 9, č. 1 (2014), s. 3687-3706. E-ISSN 1178-2013
Grant CEP: GA MZd(CZ) NT13297; GA ČR(CZ) GA106/09/1000; GA MŠMT(CZ) ED1.1.00/02.0109
Institucionální podpora: RVO:67985823 ; RVO:67985891 ; RVO:61389013
Klíčová slova: nanoparticles * hydroxyapatie * osteoblasts * composite materials
Kód oboru RIV: EI - Biotechnologie a bionika
Impakt faktor: 4.383, rok: 2014

Higher concentrations of micro-sized HA (ie. 20%-25% micro-sized HA) significantly reduced the growth and the viability of MG-63 cells. A concentration range of 5-15 vol% (HA/matrix) of both nano-sized and micro-sized HA particles seems to be the optimum for colonizing the composite with osteoblasts. These composites can potentially be used in medical applications
Trvalý link: http://hdl.handle.net/11104/0236228