Počet záznamů: 1  

Sphingolipid levels crucially modulate lateral microdomain organization of plasma membrane in living yeast

  1. 1.
    0430431 - ÚEM 2015 RIV NL eng J - Článek v odborném periodiku
    Večeř, J. - Veselá, Petra - Malínský, Jan - Herman, P.
    Sphingolipid levels crucially modulate lateral microdomain organization of plasma membrane in living yeast.
    FEBS Letters. Roč. 588, č. 3 (2014), s. 443-449. ISSN 0014-5793
    Grant CEP: GA ČR GAP205/12/0720
    Institucionální podpora: RVO:68378041
    Klíčová slova: membrane microdomain * lipid order * fluidity
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 3.169, rok: 2014

    We found significantly reduced abundance of gel-like microdomains in the plasma membrane of living Saccharomyces cerevisiae cells with compromised biosynthesis of sphingolipids. The phenotype could be reverted by the supply of exogenous dihydrosphingosine. The data indicate that organization of lateral microdomains is an essential physiological role of sphingolipids.
    Trvalý link: http://hdl.handle.net/11104/0237201