Počet záznamů: 1  

Two oxidation pathways of bioactive flavonol rhamnazin under ambient conditions

  1. 1. 0428563 - UFCH-W 2015 RIV GB eng J - Článek v odborném periodiku
    Ramešová, Šárka - Degano, I. - Sokolová, Romana
    Two oxidation pathways of bioactive flavonol rhamnazin under ambient conditions.
    Electrochimica acta. Roč. 133, JUL 2014 (2014), s. 359-363. ISSN 0013-4686
    Grant ostatní:Rada Programu interní podpory projektů mezinárodní spolupráce AV ČR M200401201
    Program:M
    Institucionální podpora: RVO:61388955
    Klíčová slova: oxidation * flavonoids * rhamnazin
    Kód oboru RIV: CG - Elektrochemie
    Impakt faktor: 4.504, rok: 2014

    Two pathways of the oxidation mechanism of rhamnazin under ambient conditions are proposed. The redox potential of rhamnazin strongly depends on the presence of dissociation forms in solution. In situ spectroelectrochemistry and identification of degradation products by HPLC-DAD and HPLC–ESI-MS/MS confirmed the presence of fast subsequent chemical reactions following the electron transfer. As demonstrated, strict anaerobic conditions have to be preserved in studies of antioxidant properties and of its pharmacological efficiency. In the absence of oxygen, 2,4-dihydroxy-2-(4 -hydroxy-3 -methoxybenzoyl)- 6-methoxy-benzofuran-3(2H)-one was identified as the only oxidation product.
    Trvalý link: http://hdl.handle.net/11104/0233907