Single cell analysis of caspase-3 in apoptotic and non-apoptotic cells during mouse limb development

0428307 - ÚIACH 2015 GB eng A - Abstrakt
Adamová, Eva - Klepárník, Karel - Matalová, E.
Single cell analysis of caspase-3 in apoptotic and non-apoptotic cells during mouse limb development.
Bone Abstracts. Roč. 3, - (2014), PP58. ISSN 2052-1219.
[European Calcified Tissue Society Congress /41./. 17.05.2014-20.05.2014, Praha]
Grant CEP: GA ČR GAP206/11/2377; GA ČR(CZ) GA14-28254S
Institucionální podpora: RVO:68081715
Klíčová slova: single cell analysis * caspase-3 * mouse limb development
Kód oboru RIV: CB - Analytická chemie, separace

Caspases belong to cysteine proteases participating in apoptosis and inflammation. However, there is recent evidence about their functions also in other events such as cell differentiation. This is supported also by our latest research of odontogenesis and osteogenesis. With the increasing interest in caspases due to their apoptosis-related therapies but also emerging non-apoptotic roles, exact evaluation of their impact at single cell level becomes challenging.
Trvalý link: http://hdl.handle.net/11104/0233657