Počet záznamů: 1  

Formation of the Tooth-Bone Interface

  1. 1.
    0425577 - UZFG-Y 2014 RIV US eng J - Článek v odborném periodiku
    Fleischmannová, Jana - Matalová, Eva - Sharpe, P. T. - Míšek, Ivan - Radlanski, R.J.
    Formation of the Tooth-Bone Interface.
    Journal of Dental Research. Roč. 89, č. 2 (2010), s. 108-115. ISSN 0022-0345
    Grant CEP: GA ČR GC524/08/J032; GA AV ČR KJB500450802
    Výzkumný záměr: CEZ:AV0Z50450515
    Klíčová slova: epithelial root sheath * periodontal ligament cells * 1st branchial arch
    Kód oboru RIV: ED - Fyziologie
    Impakt faktor: 3.773, rok: 2010

    Not only are teeth essential for mastication, but also missing teeth are considered a social handicap due to speech and aesthetic problems, with a resulting high impact on emotional well-being. Several treatment procedures are currently available for tooth replacement with mostly inert prosthetic materials and implants. Natural tooth substitution based on copying the developmental process of tooth formation is particularly challenging and creates a rapidly developing area of molecular dentistry. In any approach, functional interactions among the tooth, the surrounding bone, and the periodontium must be established. Therefore, recent research in craniofacial genetics searches for mechanisms responsible for correct cell and tissue interactions, not only within a specific structure, but also in the context of supporting structures. A tooth crown that is not functionally anchored to roots and bone is useless. This review aims to summarize the developmental and tissue homeostatic aspects of the tooth-bone interface, from the initial patterning toward tooth eruption and lifelong interactions between the tooth and its surrounding alveolar bone.
    Trvalý link: http://hdl.handle.net/11104/0231464