0422867 - ÚIACH 2014 US eng A - Abstrakt
Klepárník, Karel - Luksch, Jaroslav - Tarantová, Anna - Foret, František
Effect of electroosmotic flow on the function of liquid-junction electrospray interface between capillary electrophoresis and mass spectrometry.
61st ASMS Proceedings. Minneapolis, 2013. P057. ISBN N.
[ASMS Conference on Mass Spectrometry and Allied Topics /61./. 08.06.2013-09.06.2013, Minneapolis]
Grant CEP: GA ČR(CZ) GBP206/12/G014; GA ČR GAP206/11/2377
Institucionální podpora: RVO:68081715
Klíčová slova: microcolumn separations * capillary liquid chromatography * CE-MS instrumentation
Kód oboru RIV: CB - Analytická chemie, separace

Microcolumn separations, such as capillary liquid chromatography or capillary electrophoresis (CE) on-line combined with mass spectrometry (MS), fulfill requirements of high-resolution and sensitivity analyses of physiologically important compounds in complex mixtures of biological samples, body fluids or cell lysates. The essential part of CE-MS instrumentation is electrospray interface providing several functions: the transfer of analytes from the separation into the spray capillary, mixing with a spray liquid, pressure control of flow through the spray capillary and electrical potentials for CE separation and electrospray. It follows that the construction and optimization of the interface is not an easy task.
Trvalý link: http://hdl.handle.net/11104/0228983