Počet záznamů: 1  

Erythropoiesis- and Thrombopoiesis-Characterizing Parameters in Adenosine A(3) Receptor Knock-Out Mice

  1. 1.
    0394862 - BFU-R 2014 RIV CZ eng J - Článek v odborném periodiku
    Hofer, Michal - Pospíšil, Milan - Dušek, L. - Hoferová, Zuzana - Weiterová, Lenka
    Erythropoiesis- and Thrombopoiesis-Characterizing Parameters in Adenosine A(3) Receptor Knock-Out Mice.
    Physiological Research. Roč. 62, č. 3 (2013), s. 305-311. ISSN 0862-8408
    Grant CEP: GA ČR(CZ) GAP303/11/0128
    Institucionální podpora: RVO:68081707
    Klíčová slova: ELEVATING EXTRACELLULAR ADENOSINE * COLONY-STIMULATING FACTOR * HEMATOPOIETIC PROGENITOR CELLS
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 1.487, rok: 2013

    Influence of the regulatory system mediated by adenosine A(3) receptors on the functioning of erythropoiesis and thrombopoiesis was studied by means of evaluation of the numbers and attributes of peripheral blood erythrocytes and platelets, as well as of erythroid bone marrow progenitor cells in adenosine A(3) receptor knock-out (Adora3(tm1Jbsn)/Adora3(tm1Jbsn), A(3)AR((-/-))) mice and their wild-type C57BL/6 counterparts, both males and females. Minor but statistically significant disturbances in the properties of erythrocytes, namely in the parameters of mean erythrocyte volume and mean erythrocyte hemoglobin were observed in A(3)AR((-/-)) mice.
    Trvalý link: http://hdl.handle.net/11104/0223020