Počet záznamů: 1  

Potentiation of Inhibitory Synaptic Transmission by Extracellular ATP in Rat Suprachiasmatic Nuclei

  1. 1. 0392575 - FGU-C 2014 RIV US eng J - Článek v odborném periodiku
    Bhattacharya, Anirban - Vávra, Vojtěch - Svobodová, Irena - Bendová, Z. - Vereb, G. - Zemková, Hana
    Potentiation of Inhibitory Synaptic Transmission by Extracellular ATP in Rat Suprachiasmatic Nuclei.
    Journal of Neuroscience. Roč. 33, č. 18 (2013), s. 8035-8044. ISSN 0270-6474
    Grant CEP: GA AV ČR(CZ) IAA500110910; GA ČR(CZ) GBP304/12/G069; GA MŠk(CZ) EE2.3.30.0025
    Institucionální podpora: RVO:67985823
    Klíčová slova: suprachiasmatic nucleus * P2X receptors * P2Y receptors * ATP * GABA * spontaneous inhibitory synaptic currents
    Kód oboru RIV: ED - Fyziologie
    Impakt faktor: 6.747, rok: 2013

    The hypothalamic suprachiasmatic nuclei (SCN), the circadian master clock in mammals, releases ATP in a rhythm. In this study, we examined the expression and function of ATP-gated P2X receptors (P2XRs) in the SCN neurons of rat brain slices. Our data show that ATP activates presynaptic P2X2Rs to regulate inhibitory synaptic transmission within the SCN and that this effect varies between dorsomedial and ventrilateral SCN regions
    Trvalý link: http://hdl.handle.net/11104/0221407