Počet záznamů: 1  

Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum

  1. 1. 0387740 - MBU-M 2013 RIV GB eng J - Článek v odborném periodiku
    Busche, T. - Šilar, Radoslav - Pičmanová, Martina - Pátek, Miroslav - Kalinowski, J.
    Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum.
    BMC Genomics. Roč. 13, č. 445 (2012), s. 445-464. ISSN 1471-2164
    Grant CEP: GA ČR GC204/09/J015
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Corynebacterium glutamicum * ECF sigma factor * Anti-sigma factor
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 4.397, rok: 2012

    Background: The expression of genes in Corynebacterium glutamicum, a Gram-positive non-pathogenic bacterium used mainly for the industrial production of amino acids, is regulated by seven different sigma factors of RNA polymerase, including the stress-responsive ECF-sigma factor SigH. The sigH gene is located in a gene cluster together with the rshA gene, putatively encoding an anti-sigma factor. The aim of this study was to analyze the transcriptional regulation of the sigH and rshA gene cluster and the effects of RshA on the SigH regulon, in order to refine the model describing the role of SigH and RshA during stress response
    Trvalý link: http://hdl.handle.net/11104/0220331