Caspase 3 chemiluminiscence activity determination in apoptotic cells and design of Caspase 3 sensor

0386277 - ÚIACH 2013 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Lišková, Marcela - Klepárník, Karel - Pazdera, P. - Foret, František
Caspase 3 chemiluminiscence activity determination in apoptotic cells and design of Caspase 3 sensor.
CECE 2012. 9th International Interdisciplinary Meeting on Bioanalysis. Brno: Ústav analytické chemie AV ČR, v. v. i, 2012 - (Foret, F.; Křenková, J.; Guttman, A.; Klepárník, K.; Boček, P.), s. 344-348. ISBN 978-80-904959-1-3.
[CECE 2012. International Interdisciplinary Meeting on Bioanalysis /9./. Brno (CZ), 01.11.2012-02.11.2012]
Grant CEP: GA ČR(CZ) GAP301/11/2055; GA ČR GAP206/11/2377; GA MŠMT(CZ) EE2.3.20.0182; GA ČR GA203/08/1680
Výzkumný záměr: CEZ:AV0Z40310501
Klíčová slova: Caspase 3 * apoptosis * chemiluminescence * FRET
Kód oboru RIV: CB - Analytická chemie, separace

Apoptosis, or programmed cell death, is an essential physiological process that plays a critical role in development of tumor or autoimmune disorders. In some instances knowledges of this pathway can be used for inhibit or prevent cancer development and other diseases. One of the earliest and most consistent observed features of apoptosis is the induction of a series of cytosolic proteases – caspases.
Trvalý link: http://hdl.handle.net/11104/0215649