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Poly(2-oxazoline)s - are they more advantageous for biomedical applications than other polymers?

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    0381213 - ÚMCH 2013 RIV DE eng J - Článek v odborném periodiku
    Sedláček, Ondřej - Monnery, B. D. - Filippov, Sergey K. - Hoogenboom, R. - Hrubý, Martin
    Poly(2-oxazoline)s - are they more advantageous for biomedical applications than other polymers?
    Macromolecular Rapid Communications. Roč. 33, č. 19 (2012), s. 1648-1662. ISSN 1022-1336. E-ISSN 1521-3927
    Grant ostatní: AV ČR(CZ) M200501201
    Program: M
    Institucionální podpora: RVO:61389013
    Klíčová slova: biocompatibility * biological applications of polymers * physicochemical behavior
    Kód oboru RIV: CD - Makromolekulární chemie
    Impakt faktor: 4.929, rok: 2012

    Poly(2-alkyl-2-oxazoline)s are biocompatible polymers with polypeptide-isomeric structures that are attracting increasing interest as biomaterials for drug, gene, protein, and radionuclide delivery. They are, however, still relatively new in comparison to other classes of hydrophilic water-soluble polymers already established for such use, including poly(ethylene oxide), polyvinylpyrrolidone, and polymethacrylamides such as poly[ N -(2-hydroxypropyl) methacrylamide]. This feature article critically compares the synthetic aspects and physicochemical and biological properties of poly(2-alkyl-2-oxazoline)s and these commonly studied polymers in terms of their suitability for biomedical applications.
    Trvalý link: http://hdl.handle.net/11104/0211738

     
     
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