0380846 - BC 2013 RIV US eng J - Journal Article
Ryneš, J. - Donohoe, C. D. - Frommolt, P. - Brodesser, S. - Jindra, Marek - Uhlířová, M.
Activating transcription factor 3 regulates immune and metabolic homeostasis.
Molecular and Cellular Biology. Roč. 32, č. 19 (2012), s. 3949-3962. ISSN 0270-7306. E-ISSN 1098-5549
R&D Projects: GA ČR(CZ) GD204/09/H058
Institutional support: RVO:60077344
Keywords : metabolic homeostasis
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.372, year: 2012 ; AIS: 2.778, rok: 2012
DOI: https://doi.org/10.1128/MCB.00429-12

Using Drosophila genetics and systems biology, this study shows that the bZIP transcription factor Atf3 links metabolic and innate immune responses to safeguard homeostasis. The single fly Atf3 gene likely integrates functions of two paralogous mammalian genes.
Permanent Link: http://hdl.handle.net/11104/0211454