0379965 - ÚOCHB 2013 RIV CH eng J - Článek v odborném periodiku
Cherkupally, Prabhakar - Beier, Petr
Synthesis of N-substituted a,a-difluoro-b-aminophosphonates by addition of diethyl lithiodifluoromethylphosphonate to imines.
Journal of Fluorine Chemistry. Roč. 141, Sep (2012), s. 76-82. ISSN 0022-1139. E-ISSN 1873-3328
Grant CEP: GA ČR GP203/08/P310
Institucionální podpora: RVO:61388963
Klíčová slova: nucleophilic addition * difluorophosphonate * aminophosphonate * imines
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 1.939, rok: 2012 ; AIS: 0.487, rok: 2012
DOI: https://doi.org/10.1016/j.jfluchem.2012.06.004

Addition of diethyl lithiodifluoromethylphosphonate to N-substituted imines provides N-substituted alpha,alpha-difluoro-beta-aminophosphonates. N-Alkyl, aryl, or Boc substituted aldimines give good to high yields in these reactions, while in ketimine series, only activated N-(2,2,2-trifluoro-1-phenylethylidene)aniline showed high reactivity.
Trvalý link: http://hdl.handle.net/11104/0210806