0379095 - ÚŽFG 2013 RIV CS eng J - Článek v odborném periodiku
Kremplová, M. - Krejcová, l. - Hynek, D. - Barath, P. - Majzlík, P. - Horák, Vratislav - Adam, V. - Sochor, J. - Cernei, N. - Hubálek, J. - Vrba, R. - Kižek, R.
Automated electrochemical detection of iron ions in erythrocytes from melim minipigs suffering from melanoma.
International Journal of Electrochemical Science. Roč. 7, č. 7 (2012), s. 5893-5909. ISSN 1452-3981. E-ISSN 1452-3981
Výzkumný záměr: CEZ:AV0Z50450515
Klíčová slova: Automation * Biological sample * Electrochemical detection
Kód oboru RIV: CG - Elektrochemie
Impakt faktor: 3.729, rok: 2011 ; AIS: 0.381, rok: 2011

We focused on testing of new, fully automated electrochemical measuring system. The analyser can be used for detection and quantification of a wide range of compounds including metals, peptides, proteins, nucleic acids and drugs. To test the possibilities of suggested system, concentration of iron in blood samples of MeLiM minipigs was measured. We optimized some experimental conditions such as composition and pH of the supporting electrolyte, value of the deposition potential and preparation of erythrocytes. We found that the iron concentration in erythrocytes of the control group was significantly higher (10 µg Fe ions/ml) than in the group of animals suffering from melanoma (3.5 µg Fe ions/ml).
Trvalý link: http://hdl.handle.net/11104/0210366