Počet záznamů: 1
Electrocatalytic monitoring of metal binding and mutation-induced conformational changes in p53 at picomole level
- 1.0373453 - BFÚ 2012 RIV US eng J - Článek v odborném periodiku
Paleček, Emil - Ostatná, Veronika - Černocká, Hana - Joerger, A.C. - Fersht, A.R.
Electrocatalytic monitoring of metal binding and mutation-induced conformational changes in p53 at picomole level.
Journal of the American Chemical Society. Roč. 133, č. 18 (2011), s. 7190-7196. ISSN 0002-7863. E-ISSN 1520-5126
Grant CEP: GA AV ČR(CZ) KAN400310651; GA AV ČR(CZ) KJB100040901; GA MŠMT(CZ) LC06035
Grant ostatní: GA ČR(CZ) GAP301/11/2055
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: p53 * conformational changes * constant current chronopotentiometric stripping (CPS)
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 9.907, rok: 2011
CPS on dithiothreitol-modified mercury electrodes enabled distinguishing of wt- and mutant of the tumor suppressor p53. Moreover, it was possible to monitor the loss of an essential zinc ion.
Trvalý link: http://hdl.handle.net/11104/0206550
Počet záznamů: 1