Počet záznamů: 1  

Spatial Navigation and APOE in Amnestic Mild Cognitive Impairment

  1. 1. 0370885 - FGU-C 2012 RIV CH eng J - Článek v odborném periodiku
    Laczó, J. - Andel, R. - Vlček, Kamil - Maťoška, V. - Vyhnálek, M. - Tolar, M. - Bojar, M. - Hort, J.
    Spatial Navigation and APOE in Amnestic Mild Cognitive Impairment.
    Neurodegenerative Diseases. Roč. 8, č. 4 (2011), s. 169-177 ISSN 1660-2854
    Grant CEP: GA ČR(CZ) GA309/09/0286; GA ČR(CZ) GA309/09/1053; GA MŠk(CZ) 1M0517; GA MŠk(CZ) LC554
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: mild cognitive impairment * spatial navigation * Alzheimer's disease
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 3.056, rok: 2011

    We found more profound deficits in spatial navigation in aMCI E4 positive relative to aMCI E4 negative patients. The aMCI E4 positive group resembled the mild AD group in spatial navigation performance. Although E4 genotype was indicative of spatial navigation performance, it was not indicative of the aMCI patients’ ability to learn the tasks. Spatial navigation testing represents a promising area with respect to identifying individuals at higher risk for AD among the heterogeneous MCI population
    Trvalý link: http://hdl.handle.net/11104/0204561