Počet záznamů: 1  

Aging and longevity of yeast colony populations: metabolic adaptation and differentiation

  1. 1. 0370714 - MBU-M 2012 RIV GB eng J - Článek v odborném periodiku
    Váchová, Libuše - Palková, Z.
    Aging and longevity of yeast colony populations: metabolic adaptation and differentiation.
    Biochemical Society Transactions. Roč. 39, - (2011), s. 1471-1475 ISSN 0300-5127
    Grant CEP: GA ČR GA204/08/0718; GA MŠk(CZ) LC531
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: adaptation and longevity * ammonia signalling * quorum sensing
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 3.711, rok: 2011

    Yeast multicellular colonies possess several traits that are absent from individual yeasts. These include the ability to synchronize colony population development and adapt its metabolism to different environmental changes, such as nutrient depletion. This, together with cell diversification to cell variants with distinct metabolic and other properties, contributes to the main goal of the colony population: to achieve longevity. In this respect, a benefit to individual cells is subordinated to the benefit to the whole population, exhibiting a kind of altruistic behaviour. For example, some colony cells located at particular positions undergo regulated cell dying and provide components to other cells located in more propitious areas. The enhancement of techniques that enable the in vivo investigation of three-dimensional spatiotemporal colony development can lead to new discoveries on metabolic differentiation and regulation in the near future
    Trvalý link: http://hdl.handle.net/11104/0204429