Počet záznamů: 1
Regioselective alcoholysis of silybin A and B acetates with lipases
- 1.0363054 - MBÚ 2012 RIV NL eng J - Článek v odborném periodiku
Purchartová, Kateřina - Marhol, Petr - Gažák, Radek - Monti, D. - Riva, S. - Kuzma, Marek - Křen, Vladimír
Regioselective alcoholysis of silybin A and B acetates with lipases.
Journal of Molecular Catalysis B-Enzymatic. Roč. 71, 3-4 (2011), s. 119-123. ISSN 1381-1177
Grant CEP: GA MŠMT OC09045; GA MŠMT(CZ) ME10027; GA ČR(CZ) GAP301/11/0767
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: Silybin B * Silibinin * Silymarin
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.735, rok: 2011
Large screening identified lipase AK to be capable of the selective deacetylation of pentaacetyl silybins A and B to yield 3,5,20,23-tetra-O-acetyl-silybins A and B, and 3,20,23-tri-O-acetyl-silybins A and B, respectively. Deacetylation occurred at phenolic OH groups, only. These new compounds prepared from the optically pure silybins can serve as new stereochemically pure synthons for selective silybin modifications
Trvalý link: http://hdl.handle.net/11104/0199161
Počet záznamů: 1