ASSESSING MULTILOCUS INTROGRESSION PATTERNS: A CASE STUDY ON THE MOUSE X CHROMOSOME IN CENTRAL EUROPE

0362900 - ÚŽFG 2012 RIV US eng J - Článek v odborném periodiku
Macholán, Miloš - Baird, S. J. E. - Dufková, Petra - Munclinger, P. - Vošlajerová, Barbora - Piálek, Jaroslav
ASSESSING MULTILOCUS INTROGRESSION PATTERNS: A CASE STUDY ON THE MOUSE X CHROMOSOME IN CENTRAL EUROPE.
Evolution. Roč. 65, č. 5 (2011), s. 1428-1446. ISSN 0014-3820. E-ISSN 1558-5646
Grant CEP: GA ČR GA206/08/0640
Výzkumný záměr: CEZ:AV0Z50450515; CEZ:AV0Z60930519
Klíčová slova: genetic conflict * hybrid zone movement * Mus musculus musculus
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 5.146, rok: 2011

Multilocus hybrid zone (HZ) studies predate genomics by decades. The power of early methods is becoming apparent and now large datasets are commonplace. Relating introgression along a chromosome to evolutionary process is challenging: although reduced introgression regions may indicate speciation genes, this pattern may be obscured by asymmetric introgression of linked invasive genes. Further, HZ movement may form salients and leave islands in its wake. Barton's concordance was proposed 24 years ago for assessing introgression where geographic patterns are complex. The geographic axis of introgression is replaced with the hybrid index. We compare this, a recently proposed genomic clines approach, and two-dimensional (2D) geographic analyses, for 24 X chromosome loci of 2873 mice from the central-European house mouse HZ. In 2D, 14 loci show linear contact, seven precisely matching previous studies.
Trvalý link: http://hdl.handle.net/11104/0199074