Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells

0359402 - ÚOCHB 2012 RIV US eng J - Článek v odborném periodiku
Topalis, D. - Lebeau, I. - Krečmerová, Marcela - Andrei, G. - Snoeck, R.
Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells.
Antimicrobial Agents and Chemotherapy. Roč. 55, č. 5 (2011), s. 1961-1967. ISSN 0066-4804. E-ISSN 1098-6596
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: polyomavirus * BK virus * nephropathy * acyclic nucleoside phosphonates * HPMP-5-azaC
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 4.841, rok: 2011

Evaluation of three different classes of acyclic nucleoside phosphonates for their activities against BK virus replication was performed. HPMPC, HPMP-5-azaC, its cyclic form and HDE ester of its cyclic form were found the most selective inhibitors of BKV replication in primary human renal cells.
Trvalý link: http://hdl.handle.net/11104/0197199