Oxidative stress and chromosomal aberrations in an environmentally exposed population

0358218 - ÚEM 2011 RIV NL eng J - Článek v odborném periodiku
Rössner ml., Pavel - Rössnerová, Andrea - Šrám, Radim
Oxidative stress and chromosomal aberrations in an environmentally exposed population.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 707, 1-2 (2011), s. 34-41. ISSN 0027-5107
Grant CEP: GA MŽP(CZ) SP/1B3/8/08
Výzkumný záměr: CEZ:AV0Z50390512
Klíčová slova: air pollution * oxidative stress * chromosomal aberrations
Kód oboru RIV: DN - Vliv životního prostředí na zdraví
Impakt faktor: 2.850, rok: 2011

The effect of seasonal variability of environmental air pollutants (c-PAHs and particulate matter PM2.5) on oxidative stress and cytogenetic biomarkes in a group of city policement from Prague was investigated. No significant difference between the two seasons (February and May 2007) for any biomarkers of oxidative stress (8-oxodG, 15-F2t-IsoP) or any cytogenetic parameter (genomic frequency of translocations – FG/100; % AB.C.; or the number of acentric fragments – ace) was observed. The effects of air pollution on all subjects regardless of the season was also studied. In summary, the results indicate that the exposure to environmental pollutants affects urinary excretion of 8-oxodG, lipid peroxidation and the frequency of chromosomal aberrations.
Trvalý link: http://hdl.handle.net/11104/0196315